
Sole Centro de Imagen
Polynucleotides in Nerja
Biostimulation that regenerates skin and improves dark circles, texture and elasticity naturally.
What are polynucleotides?
Polynucleotides are naturally derived DNA fragments, highly purified and biocompatible (usually derived from salmon), used in aesthetic medicine as powerful biostimulators for deep tissue regeneration. They stimulate fibroblasts to produce collagen, elastin and hyaluronic acid, improving skin firmness, hydration and texture without adding volume.
Thanks to their biostimulating action, they work in the deeper layers, activating regenerative processes that restore skin firmness and vitality without adding volume or altering facial expression.
This treatment is ideal both for preventing ageing and for treating visible signs such as dehydration, fine lines or loss of density. It is particularly recommended for thin, dull or marked skin, as it improves overall tissue quality and enhances radiance. As a minimally invasive and well-tolerated option, it allows you to return to your usual routine as normal after the session.

Benefits
These compounds can stimulate the production of collagen, elastin and hyaluronic acid, improve microcirculation, combat oxidative stress and increase cellular hydration. The result is firmer, more elastic and radiant skin with improved texture. The treatment is ideal for addressing skin laxity, fine lines, dehydrated skin, acne marks and signs of ageing without altering facial features.
Stimulates cellular regeneration from within
Improves skin firmness, elasticity and density
Provides deep, long-lasting hydration
Reduces fine lines and expression lines
Improves skin texture, tone and radiance
Promotes healing and reduces acne marks
Increases skin oxygenation and microcirculation
Biocompatible, safe and suitable for sensitive skin
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Before & after
Real results from our own patients. No retouching — just protocol, technique and follow-up.
BeforeAfter
BeforeAfter
How is polynucleotide treatment carried out?
The treatment is carried out using intradermal microinjections, with very fine needles or a cannula, in areas such as the face, neck, décolletage or even around the eyes.

Initial assessment
The doctor assesses your skin and its needs to determine the areas to treat and the amount of product to use.

Procedure
Microinjections distribute the polynucleotides into the dermis, promoting cellular repair and collagen production.

Recovery
Mild redness or swelling subsides within hours. Daily activities can be resumed immediately.

Results
Firmer, more hydrated and radiant skin, with progressive improvements in texture and elasticity over the following weeks.
Start with a personalised assessment
Before starting we look at your case and explain what result is realistic and how many sessions you will need. No obligation.
Frequently asked questions
Your questions about this treatment, your medical assessment and aftercare.
What benefits does it offer compared with other rejuvenation treatments?
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Polynucleotides regenerate the skin from within without adding volume, improving skin quality with natural-looking, lasting and progressive results.
Which skin types is it recommended for?
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Suitable for all skin types, especially those showing signs of ageing, dehydration, laxity or loss of elasticity.
Which areas can be treated?
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The face, neck, décolletage, hands and area around the eyes, helping to improve skin texture, firmness and quality.
How do polynucleotides work in the skin?
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They stimulate cellular regeneration and collagen production and improve deep hydration, providing a progressive rejuvenating effect.
How many sessions are needed?
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Generally, 3–4 sessions spaced weeks apart are recommended, with maintenance every 6–12 months depending on your skin.
When do results start to become noticeable?
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Improved hydration and radiance can be noticed from the first session, with maximum effects developing over the following weeks.
Is the treatment painful?
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The microinjections may cause mild discomfort, but a topical anaesthetic is used for greater comfort.
How long do the effects last?
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Results can last between six months and a year, depending on skin type and aftercare.
Can they be combined with other treatments?
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Yes, they can be combined with neuromodulators, fillers, radiofrequency or peels to enhance rejuvenation.
What aftercare should I follow?
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Avoid direct sun exposure, extreme heat and make-up for 24 hours, and use sunscreen and keep your skin hydrated.

Your doctor at Sole
Dr. Miguel Iván Villar Mena
Master's degree in Aesthetic Medicine · Registered doctor no. 292909087
Before any medical treatment he sees you in consultation, assesses your case and explains clearly what result you can expect, how many sessions you need and the aftercare.
Licensed medical centre · NICA 36.364
More medical treatments
All our medical treatments follow a personal assessment in a licensed medical centre (NICA 36.364).
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Reviews
What our clients say
“Everything perfect, as always. Exquisite care and results you notice from the first session.”
“Professional, warm and excellent service. They explain every step of the treatment in detail.”
“I have been coming for years and love every treatment. The best centre in Nerja.”
Request information
Questions about this treatment?
Leave your details and we will reply personally to answer your questions or book your assessment.
Polynucleotides
Areas we serve
Polynucleotides at our centre in Nerja
We offer polynucleotides on Avenida de la Constitución in Nerja. If you are travelling from Torrox, Torre del Mar, Málaga, La Herradura, Almuñécar, Salobreña, Motril or elsewhere in the Axarquía or Costa Tropical, contact us to discuss service options and arrange your appointment before travelling. All services take place at our centre in Nerja.
- Nerja
- Maro
- Frigiliana
- Torrox
- Torrox Costa
- Algarrobo
- Torre del Mar
- Vélez-Málaga
- Cómpeta
- Rincón de la Victoria
- Málaga
- La Herradura
- Almuñécar
- Salobreña
- Motril

